Fig. 4From: The 55-kD Tumor Necrosis Factor Receptor and CD95 Independently Signal Murine Hepatocyte Apoptosis and Subsequent Liver Failure Hepatotoxicity of Con A or ActD/TNF in wt or lpr MRL/MpJ mice Animals were injected intravenously with 25 mg/kg Con A or saline or a combination of 3.3 µg/kg TNF i.v. with 800 µg/kg ActD i.p. Hepatotoxicity was determined after 8 hr by the measurement of plasma ALT in blood obtained by cardiac puncture. Data are means ± SD, n = 3.Back to article page