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Fig. 2 | Molecular Medicine

Fig. 2

From: Retroviral Vector Design for Gene Therapy of Cancer: Specific Inhibition and Tagging of BCR-ABLp190 Cells

Fig. 2

(A) Specific growth inhibition of Ba/F3+p190 cells infected with the MFGA190CD5 retrovirus following IL-3 withdrawal, and (B) The viability of Ba/F3+p210 cells is not affected by MFGA190CD5 virus

(A) Ba/F3+p190 cells were infected with recombinant MFGA190CD5 (left panels) or MFGS190CD5 (right panels). The viability of infected cells was assessed by staining with anti-human CD5 antibody in the absence of IL-3 (bottom panels). (B) Ba/F3+p210 cells were infected with the virus encoding BCR-ABLp190 antisense transcripts and the truncated human CD5 surface marker. Infected cells (left panel) were assessed by their viability after IL-3 withdrawal (right panel).

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Molecular Medicine

ISSN: 1528-3658