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Fig. 1 | Molecular Medicine

Fig. 1

From: High Prion and PrPSc Levels but Delayed Onset of Disease in Scrapie-Inoculated Mice Heterozygous for a Disrupted PrP Gene

Fig. 1

Symptom-free and surviving Prn-p+/+, Prn-p0/+, and Prn-p0/+/SHaPrP0/+ mice after inoculation with mouse or hamster prions

Inoculations were as described in Experimental Procedures. (A) Thirty-one Prn-p+/+ and 19 Prn-p0/+ mice after inoculation with mouse RML prions. (B) Fifteen Prn-p0/+/SHaPrP0/+ mice after inoculation with mouse RML prions. (C) Eight Prn-p0/+ and 9 Prn-p0/+/SHaPrP0/+ mice after inoculation with hamster Sc237 prions.

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