Table 1 Incubation times to onset of disease and death

Prn-p ^{+/+ a}

Disease

158 ± 11

ND (>600)

Death

171 ± 11

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Prn-p ^0/+

Disease

290 ± 33 (n = 19)

>600 (n = 9)

Death

415 ± 30 (n = 15)

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Prn-p^0/+/SHaPrP^0/+

Disease

260 ± 22 (n = 15)^b

67 ± 4 (n = 9)

Death

280 ± 23 (n = 12)

72 ± 7 (n = 6)

Prn-p^0/0/SHaPrP^0/+

Disease

323 ± 60 (n = 18)

58 ± 2 (n = 6)^c

Death

341 ± 60 (n = 16)

60 ± 5 (n = 9)

Prn-p ^0/0

Disease

>600 (n = 10)

>600 (n = 5)

Death

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