Table 1 Cell surface phenotype of human peripheral blood fibrocytes (subpopulation reactivity compiled from (12))
From: Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair
Antigen | Cell Subpopulations | |
|---|---|---|
Positive Expression | ||
Vimentin | Intermediate filament | Fibrobasts |
Fibronectin | Pericellular Matrix | Mesenchymal cells, lymphoid cells |
Collagen I | Extracellular matrix | Fibroblasts |
Collagen III | Extracellular matrix | Fibroblasts |
CD11b | Adhesion molecule | Monocytes, granulocytes, NK cells |
CD13 | Aminopeptidase N | Myeloid and dendritic cells |
CD18 | Integrin β2 | Lymphoid and myeloid cells |
CD34 | Precursor antigen | Hematopoietic progenitors, embryonic fibroblasts |
CD45 | Leukocytes Common Antigen | Leukocytes |
CD71 | Transferrin receptor | Macrophages, activated cells |
Negative Expression | ||
Esterase | Lysosomal enzyme | Monocytes and granulocytes |
TCR (αβ, γδ) | Antigen receptor | T-Cells |
Cytokeratin | Matrix protein | Epithelial cells |
von Willebrand | Coagulation factor | Endothelial cells and platelets |
Desmin | Intermediate filament | Muscle cells |
α-Actin | Cytoskeletal protein | Smooth muscle cells |
Laminin | Matrix protein | Blood vessels, muscle cells, nerve, etc. |
CD3 | TCR-associated antigen | T-Cells |
CD4 | Class II recognition | Helper/inducer T-cells |
CD8 | Class I recognition | Cytotoxic/suppressor T-cells |
CD10 | Endopeptidase (CALLA) | B-cell subpopulations |
CD11a | LFA-1 antigen | Lymphoid and myeloid cells |
CD14 | LBP receptor | Monocytes/macrophages |
CD16 | FcγRIII (Ig receptor) | Monocytes, granulocytes, NK cells |
CD19 | B-cell antigen | B-cells |
CD25 | IL-2 receptor | Activated macrophages/T-/B-cells |
CD33 | Pan-myeloid antigen | Myeloid and monocytic cells |
CD38 | T10 antigen | Precursor cells, activated T-/B-cells |
CD44 | Lymphocytes homing receptor | Leukocytes and erythrocytes |
CD54 | ICAM-1 | Monocytes and lymphocytes |
CD56 | NCAM | NK and T-cell subpopulations |