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Fig. 4 | Molecular Medicine

Fig. 4

From: Reciprocal Changes in the Expression of Transcription Factors GATA-4 and GATA-6 Accompany Adrenocortical Tumorigenesis in Mice and Humans

Fig. 4

Immunohistochemistry for GATA-4 in human adrenal tissue. H&E staining and immunoperoxidase staining for GATA-4 from consecutive sections of adrenocortical carcinomas (A, B), normal adrenal cortex (D, E), adenomas (F, G) and pheochromocytomas (H, I); (C) control staining with nonimmune serum (ACC). GATA-4 protein is abundantly present in the nuclei of carcinoma cells (A-C, arrowheads), but absent from normal cortex, adenomas, and pheochromocytomas. Original magnifications (×200) for (A–C), bar = 50 µm; (×100) for (D–I), bar = 100 µm.

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Molecular Medicine

ISSN: 1528-3658