Fig. 2
From: Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine
STA-improved relaxation was dependent on endothelium-derived NO. Rat thoracic artery rings were incubated with STA (10 μM) for 12 h and exposed to L-NAME (100 μM), indomethacin (1 μM) (a), 1400 W (100 nM) or ODQ (3 μM) (c) for 30 min before the PE-contraction and ACh-induced relaxation. b and d Representative traces of endothelium-dependent relaxations as in (a and c). Data were shown as mean ± SEM; n = 5, *P < 0.05 vs. Vehicle