Fig. 7From: Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteineSchematic model of the effect of STA on Hcy-induced endothelial dysfunction. Stachydrine ameliorated Hcy-induced endothelial dysfunction via Nrf2-dependent up-regulation of GTPCH1 and DHFR. The de novo synthesis and salvage of BH4 reversed eNOS uncoupling and increased NO production, thus, leading to improved endothelium-dependent vasorelaxationBack to article page