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Fig. 7 | Molecular Medicine

Fig. 7

From: RETRACTED ARTICLE: Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia

Fig. 7

Decreased expression of cAMP, PKA, CREB1 and p-CREB1 in hippocampal tissues of mice with shCREB1–1 or/and H89, Notes: A, the histogram of the mRNA expressions of cAMP, PKA and CREB1 in hippocampal tissues of mice in each group; B, The histogram of the expressions of cAMP, PKA and CREB1 in hippocampal tissues of mice in each group; C, Gray value of cAMP, PKA and CREB1 protein bands; *, p < 0.05, compared with the normal group; #, p < 0.05, compared with the VD group; cAMP, cyclic adenosine monophosphate; PKA, protein kinase A; CREB1, cyclic adenosine monophosphate responsive element-binding protein 1; VD, vascular dementia

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