Fig. 4
From: Assessment of HIF-1α expression and release following endothelial injury in-vitro and in-vivo
Concentration response curve showing (a) HIF-1α levels and (b) fold change in VEGF gene expression in cell lysates after treating rat aortic endothelial cells with different concentrations of DMOG (0–500 uM). Cells incubated at 21% O2 were used as the untreated control group and cells incubated at 1% O2 were used as a positive control for HIF-1α induction. The data are mean ± SEM of 6 independent experiments (triplicates in each experiment) where * P < 0.05, **P < 0.01 and ***P < 0.001