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Fig. 4 | Molecular Medicine

Fig. 4

From: The interplay between AR, EGF receptor and MMP-9 signaling pathways in invasive prostate cancer

Fig. 4

Evaluation of the effect of overexpression of AR in the presence or absence of DHT treatment on MMP-9 and EGFR expression in PCa cells. a Immunoblot analysis was performed to examine the expression of MMP-9 in VCaP cells that were transfected with pCMV control or pCMV-AR vectors followed by treatment with DHT or vehicle control. b Immunoblot analysis on the expression of AR in PC-3 cells that were transfected with pCMV control or pCMV-AR vectors followed by treatment with DHT. c Immunoblot analysis on the expression of MMP-9 in PC-3 cells that were transfected with pCMV control or pCMV-AR vectors followed by treatment with DHT. d Immunoblot analysis on the expression of EGFR in PC-3 cells that were transfected with pCMV control or pCMV-AR vectors followed by treatment with DHT. Data presented is the average of at least two independent experiments (±SD). p < 0.05 is indicated by “*”, p ≤ 0.01 is indicated by “**”, p ≤ 0.001 is indicated by “***”

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