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Fig. 1 | Molecular Medicine

Fig. 1

From: Circular RNA CEP128 acts as a sponge of miR-145-5p in promoting the bladder cancer progression via regulating SOX11

Fig. 1

CircCEP128 and SOX11 are up-regulated in bladder cancer. a The cluster heatmap showed some of the differentially expressed circRNAs over 2-fold change between tumor tissues and adjacent normal tissues. Red color indicates high expression level, and green color indicates low expression level. The red arrow indicates hsa_circ_0102722 (circCEP128). b The cluster heat map showed some of the differentially expressed mRNAs over 2-old change in tumor tissues and adjacent normal tissues. The red arrow indicates SOX11. c Immunochemistry staining showed more SOX11-positive cells in tumor tissues than in adjacent normal tissues. Scale bar, 50 μm. **P < 0.01, compared with adjacent tissues. d CircCEP128 and SOX11 were highly expressed in tumor tissues. **P < 0.01, compared with adjacent tissues. e According to the results of qRT-PCR, circCEP128 and SOX11 were positively related in cancer tissues and in cancer adjacent tissues

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Molecular Medicine

ISSN: 1528-3658