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Fig. 6 | Molecular Medicine

Fig. 6

From: Circular RNA CEP128 acts as a sponge of miR-145-5p in promoting the bladder cancer progression via regulating SOX11

Fig. 6

Effects of circCEP128 on cell proliferation. MTT assay was also performed to assess cell proliferation after transfection with si-circRNA of circCEP128, miR-145-5p mimics, si-SOX11, co-transfection with si-circRNA and the miR-145-5p inhibitor and co-transfection with si-SOX11 and the miR-145-5p inhibitor (a) in TCCSUP and (b) in BIU-87. Knockdown of circCEP128 inhibited cell proliferation. *P < 0.05, compared with NC. Cell apoptosis was analyzed using flow cytometry (c) in TCCSUP and (d) in BIU-87 with double staining of PI and Annexin V-FITC. Knockdown of circCEP128 induced the increased cell apoptosis rate. **P < 0.05, compared with NC

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