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Fig. 2 | Molecular Medicine

Fig. 2

From: Over-expressed microRNA-181a reduces glomerular sclerosis and renal tubular epithelial injury in rats with chronic kidney disease via down-regulation of the TLR/NF-κB pathway by binding to CRY1

Fig. 2

Bar graph shows the 24-h urinary protein level at the end of the 4th week after transfection in each group, demonstrating that up-regulated miR-181a or down-regulated CRY1 leads to the reduction of urinary protein levels in CKD. Notes: *, p < 0.05 vs. the normal group; #, p < 0.05 vs. the blank and NC groups; the data are presented as the mean ± standard deviation, analyzed by one-way ANOVA; the experiment was independently repeated three times; CRY1, cryptochrome 1; miR-181a, microRNA-181a; CKD, chronic kidney disease; NC, negative control

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Molecular Medicine

ISSN: 1528-3658