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Fig. 4 | Molecular Medicine

Fig. 4

From: Over-expressed microRNA-181a reduces glomerular sclerosis and renal tubular epithelial injury in rats with chronic kidney disease via down-regulation of the TLR/NF-κB pathway by binding to CRY1

Fig. 4

HE staining of kidney tissues (× 400) reveals that the up-regulation of miR-181a or down-regulation of CRY1 reduces the degree of CKD. Notes: the arrows indicate glomeruli; a HE staining results in renal tissues (x 400); b renal interstitial lesion score. *, p < 0.05 vs. the normal group; #, p < 0.05 vs. the blank and NC groups; the data are presented as the mean ± standard deviation, analyzed by one-way ANOVA; the experiment was independently repeated three times; HE, hematoxylin-eosin; NC, negative control; miR-181a, microRNA-181a; CRY1, cryptochrome 1

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Molecular Medicine

ISSN: 1528-3658