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Fig. 5 | Molecular Medicine

Fig. 5

From: Over-expressed microRNA-181a reduces glomerular sclerosis and renal tubular epithelial injury in rats with chronic kidney disease via down-regulation of the TLR/NF-κB pathway by binding to CRY1

Fig. 5

PASM staining (× 400) shows that up-regulated miR-181a or down-regulated CRY1 reduces the GSI. Notes: Panel a, results of PASM staining under a microscope; Panel b, histogram of PASM results; *, p < 0.05 vs. the normal group; #, p < 0.05 vs. the blank and NC groups; the data are presented as the mean ± standard deviation, analyzed by one-way ANOVA; the experiment was independently repeated three times; NC, negative control; miR-181a, microRNA-181a; CRY1, cryptochrome 1; GSI, glomerulosclerosis index; PASM, periodic Schiff-methenamine

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Molecular Medicine

ISSN: 1528-3658