Skip to main content

Table 1 SAA receptor interactions

From: Serum amyloid A – a review

Receptor Function References
SR-B1 Cholesterol efflux, clears SAA Tomita et al. (2015); He et al. (2003, 2006); Ye and Sun (2017); van der Westhuyzen et al. (2005); Cai et al. (2005)
FPRL1 Stimulates MMP-9 Badolato et al. (1994, 1995); Gao and Murphy (1993); Fiore et al. (1994); Su et al. (1999); Patel et al. (1998); Furlaneto and Campa (2000); Dufton et al. (2010); Ji et al. (2015)
FPR2 Phagocyte migration; antiapoptotic de Buck et al. (2016); Gao and Murphy (1993); Furlaneto and Campa (2000); Ye and Sun (2017); Chen et al. (2014)
TLR2 Induce IRZF7, IRF4-jmjd3; M2 markers (IL-33, IL-10, IL-1m) de Buck et al. (2016); Ray et al. (2006); He et al. (2006, 2007); Cheng et al. (2008); Ji et al. (2015); Ye and Sun (2017); Rosenthal et al. (1976); Chen and Moller (2010)
TLR4 Activate NF-κB, AP-1→NOS Hiratsuka et al. (2008); de Buck et al. (2016); Sandri et al. (2008); Deguchi et al. (2013); Li et al. (2015); Ye and Sun (2017); Poltorak et al. (1998)
RAGE Activate NF-κB, induce cytokines Li et al. (2015); Yan et al. (2000); Rὄcken et al. (2003); Kennel et al. (2016); Ye and Sun (2017)
Bacteria Opsonize Gram negative species Hari-Dass et al. (2005); Shah et al. (2006); Ye and Sun (2017)