Table 1 SAA receptor interactions
Receptor | Function | References |
|---|---|---|
SR-B1 | Cholesterol efflux, clears SAA | Tomita et al. (2015); He et al. (2003, 2006); Ye and Sun (2017); van der Westhuyzen et al. (2005); Cai et al. (2005) |
FPRL1 | Stimulates MMP-9 | Badolato et al. (1994, 1995); Gao and Murphy (1993); Fiore et al. (1994); Su et al. (1999); Patel et al. (1998); Furlaneto and Campa (2000); Dufton et al. (2010); Ji et al. (2015) |
FPR2 | Phagocyte migration; antiapoptotic | de Buck et al. (2016); Gao and Murphy (1993); Furlaneto and Campa (2000); Ye and Sun (2017); Chen et al. (2014) |
TLR2 | Induce IRZF7, IRF4-jmjd3; M2 markers (IL-33, IL-10, IL-1m) | de Buck et al. (2016); Ray et al. (2006); He et al. (2006, 2007); Cheng et al. (2008); Ji et al. (2015); Ye and Sun (2017); Rosenthal et al. (1976); Chen and Moller (2010) |
TLR4 | Activate NF-κB, AP-1→NOS | Hiratsuka et al. (2008); de Buck et al. (2016); Sandri et al. (2008); Deguchi et al. (2013); Li et al. (2015); Ye and Sun (2017); Poltorak et al. (1998) |
RAGE | Activate NF-κB, induce cytokines | Li et al. (2015); Yan et al. (2000); Rὄcken et al. (2003); Kennel et al. (2016); Ye and Sun (2017) |
Bacteria | Opsonize Gram negative species | Hari-Dass et al. (2005); Shah et al. (2006); Ye and Sun (2017) |