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Fig. 10 | Molecular Medicine

Fig. 10

From: The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9

Fig. 10

Down-regulation of SOX9 inhibited the growth of tumor in vivo a the tumor specimen figure of nude mice. b statistics of tumor volume, the growth of si-MALAT1 group and si-SOX9 group was the slowest, and the volume was the smallest. The tumor volume of NC group and si-SOX9 + miR-145 inhibitor group, si-MALAT1 + pCDNA3-SOX9 group was comparative. pcDNA3.1-SOX9 group had the largest tumor volume. c Statistical results showed that tumor weight in nude mice, the tumor weight was significantly reduced in si-MALAT1 group. d The relative miR-145 expression was conspicuously increased in si-MALAT1 group in tumor tissues. e, f The qRT-PCR and western blot showed SOX9 expression was significantly decreased in si-MALAT1 group in tumor tissues. **P < 0.01, compared with NC group

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