Skip to main content
Fig. 2 | Molecular Medicine

Fig. 2

From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Fig. 2

MiR-31 caused oxidative damage and affected the levels of inflammatory factors in intestinal tissue of rats. a content of MDA increased after treating with miR-31 mimic; (b) SOD activity was inhibited by miR-31 mimic; (c) elevated levels of TNF-α after the treatment of miR-31 mimic; (d) increased levels of IL-6 following the treatment of miR-31 mimic; (e), increased levels of IL-10 by miR-31 mimic; *, p < 0.05, vs. the sham group; #, p < 0.05, vs. the sepsis group; MDA malondiadehyde, SOD superoxidedismutase, NC negative control, TNF tumor necrosis factor, IL interleukin

Back to article page

Molecular Medicine

ISSN: 1528-3658