Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Fig. 5

MiR-31 affects oxidative damage and the levels of inflammatory factors in intestinal tissue of rats by regulating HMOX1. a siRNA-HMOX1 increased content of MDA; (b), SOD activity was down-regulated by siRNA-HMOX1; (c) increased levels of TNF-α after the treatment of siRNA-HMOX1; (d) increased levels of IL-6 following the treatment of siRNA-HMOX1; (e) increased levels of IL-10 by siRNA-HMOX1; *, p < 0.05, vs. the NC group; MDA, malondiadehyde; SOD, superoxidedismutase; NC negative control, TNF tumor necrosis factor, IL interleukin

Back to article page

Molecular Medicine

ISSN: 1528-3658