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Table 2 Intestinal barrier function of the rats is affected by miR-31

From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Group

FITC-DX (μg/mL)

Numbers

Visceral organ

Bacterial translocation rate (%)

   

Liver

Spleen

Mesenteric lymph node

 

Sham

0.27 ± 0.01

5

0

0

1

6.67%

Sepsis

1.93 ± 0.13*

5

3

3

4

66.67%*

NC

1.99 ± 0.14*

5

5

3

3

73.33%*

miR-31 mimic

2.71 ± 0.19*#

5

4

5

5

93.33%*

miR-31 inhibitor

0.78 ± 0.06*#

5

5

2

2

40.00*

  1. Notes: *, p < 0.05, vs. the sham group; #, p < 0.05, vs. the sepsis group; NC negative control