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Table 2 Intestinal barrier function of the rats is affected by miR-31

From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Group FITC-DX (μg/mL) Numbers Visceral organ Bacterial translocation rate (%)
    Liver Spleen Mesenteric lymph node  
Sham 0.27 ± 0.01 5 0 0 1 6.67%
Sepsis 1.93 ± 0.13* 5 3 3 4 66.67%*
NC 1.99 ± 0.14* 5 5 3 3 73.33%*
miR-31 mimic 2.71 ± 0.19*# 5 4 5 5 93.33%*
miR-31 inhibitor 0.78 ± 0.06*# 5 5 2 2 40.00*
  1. Notes: *, p < 0.05, vs. the sham group; #, p < 0.05, vs. the sepsis group; NC negative control