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Table 3 MiR-31 influences intestinal barrier function of the rats by regulating HMOX1

From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Group

FITC-DX (μg/mL)

Numbers

Visceral organ

Bacterial translocation rate (%)

   

Liver

Spleen

Mesenteric lymph node

 

NC

1.99 ± 0.14

5

5

3

3

73.33%

siRNA-HMOX1

2.83 ± 0.21*

5

5

5

5

100%*

miR-31 inhibitor + siRNA-HMOX1

1.96 ± 0.11

5

5

2

3

66.67%

  1. Note: *, p < 0.05, vs. the NC group; NC negative control, HMOX1 heme oxygenase 1