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Table 3 MiR-31 influences intestinal barrier function of the rats by regulating HMOX1

From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Group FITC-DX (μg/mL) Numbers Visceral organ Bacterial translocation rate (%)
    Liver Spleen Mesenteric lymph node  
NC 1.99 ± 0.14 5 5 3 3 73.33%
siRNA-HMOX1 2.83 ± 0.21* 5 5 5 5 100%*
miR-31 inhibitor + siRNA-HMOX1 1.96 ± 0.11 5 5 2 3 66.67%
  1. Note: *, p < 0.05, vs. the NC group; NC negative control, HMOX1 heme oxygenase 1