From: Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis
Group
FITC-DX (μg/mL)
Numbers
Visceral organ
Bacterial translocation rate (%)
Liver
Spleen
Mesenteric lymph node
NC
1.99 ± 0.14
5
3
73.33%
siRNA-HMOX1
2.83 ± 0.21*
100%*
miR-31 inhibitor + siRNA-HMOX1
1.96 ± 0.11
2
66.67%