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Fig. 1 | Molecular Medicine

Fig. 1

From: Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production

Fig. 1

Treatment with increasing concentrations of Calcitriol does not affect the transcription and expression levels of HBV genes and cccDNA. HepG2 cells were transfected with the 1.3 X HBV-Luc plasmid. 24 h later, the cells were treated with increasing concentrations of Calcitriol or EtOH, as a control. After an additional 24 h, the cells were harvested and analyzed for Luciferase activity (a). HBV-RNA (b), HBX (c) and cccDNA (d) were measured using RT-PCR. Results are expressed as mean ± standard deviation

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Molecular Medicine

ISSN: 1528-3658