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Table 2 Behavioral changes at different time points for mice among seven groups

From: Suppressed microRNA-96 inhibits iNOS expression and dopaminergic neuron apoptosis through inactivating the MAPK signaling pathway by targeting CACNG5 in mice with Parkinson’s disease

  Number Before injection 7 d after injection 10 d after injection 12 d after injection 14 d after injection
Normal group 10 8.06 ± 0.71 8.22 ± 0.80 8.17 ± 0.75 8.19 ± 0.86 8.63 ± 0.53
PD group 10 8.46 ± 0.36 6.55 ± 0.63* 6.05 ± 0.35* 6.51 ± 0.81* 7.11 ± 0.68*
NC group 10 8.39 ± 0.70 6.56 ± 0.71* 6.09 ± 0.49* 6.55 ± 0.50* 7.06 ± 0.81*
miR-96 mimic group 10 8.07 ± 0.37 4.38 ± 0.74*# 4.23 ± 0.35*# 4.27 ± 0.27*# 5.54 ± 0.62*#
miR-96 inhibitor group 10 8.11 ± 0.16 3.22 ± 0.71*# 3.06 ± 0.44*# 3.19 ± 0.32*# 4.13 ± 0.59*#
CACNG5 group 10 8.25 ± 0.21 3.56 ± 0.17*# 3.41 ± 0.46*# 3.37 ± 0.18*# 4.15 ± 0.45*#
miR-96 mimic + CACNG5 group 10 8.30 ± 0.69 6.36 ± 0.66* 6.06 ± 0.73* 6.60 ± 0.78* 7.03 ± 0.67*
  1. Note: The test was repeated three times independently, and the one-way ANOVA analysis was used for comparison among multiple groups (n = 10)
  2. PD Parkinson disease, NC Negative control, miR-96 microRNA-96, CACNG5 Calcium voltage-gated channel auxiliary subunit gamma 5, d Day
  3. *P < 0.05 compared with the normal group, #, P < 0.05 compared with the PD group