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Table 2 Behavioral changes at different time points for mice among seven groups

From: Suppressed microRNA-96 inhibits iNOS expression and dopaminergic neuron apoptosis through inactivating the MAPK signaling pathway by targeting CACNG5 in mice with Parkinson’s disease

 

Number

Before injection

7 d after injection

10 d after injection

12 d after injection

14 d after injection

Normal group

10

8.06 ± 0.71

8.22 ± 0.80

8.17 ± 0.75

8.19 ± 0.86

8.63 ± 0.53

PD group

10

8.46 ± 0.36

6.55 ± 0.63*

6.05 ± 0.35*

6.51 ± 0.81*

7.11 ± 0.68*

NC group

10

8.39 ± 0.70

6.56 ± 0.71*

6.09 ± 0.49*

6.55 ± 0.50*

7.06 ± 0.81*

miR-96 mimic group

10

8.07 ± 0.37

4.38 ± 0.74*#

4.23 ± 0.35*#

4.27 ± 0.27*#

5.54 ± 0.62*#

miR-96 inhibitor group

10

8.11 ± 0.16

3.22 ± 0.71*#

3.06 ± 0.44*#

3.19 ± 0.32*#

4.13 ± 0.59*#

CACNG5 group

10

8.25 ± 0.21

3.56 ± 0.17*#

3.41 ± 0.46*#

3.37 ± 0.18*#

4.15 ± 0.45*#

miR-96 mimic + CACNG5 group

10

8.30 ± 0.69

6.36 ± 0.66*

6.06 ± 0.73*

6.60 ± 0.78*

7.03 ± 0.67*

  1. Note: The test was repeated three times independently, and the one-way ANOVA analysis was used for comparison among multiple groups (n = 10)
  2. PD Parkinson disease, NC Negative control, miR-96 microRNA-96, CACNG5 Calcium voltage-gated channel auxiliary subunit gamma 5, d Day
  3. *P < 0.05 compared with the normal group, #, P < 0.05 compared with the PD group