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Table 3 Hematological assessment of pregnant mice

From: Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

(a) Red blood cell count and analysis
  RBC (× 1012/L) HGB (g/L) HCT (%) MCV (fL) MCH (pg) MCHC (g/L) RDW (%)
NP 9.2 ± 0.6 145.7 ± 10.4 42.8 ± 2.8 46.5 ± 1.6 15.9 ± 0.6 340.3 ± 4.8 21.7 ± 1.2
A30E 8.1 ± 0.7* 125.1 ± 11.2* 37.7 ± 2.7* 46.9 ± 2.3 15.5 ± 0.6 331.9 ± 7.6 22.6 ± 2.1
A30L 8.2 ± 0.7* 126.6 ± 9.9* 38.2 ± 2.4* 46.9 ± 2.2 15.5 ± 0.5 331.3 ± 10.8 21.3 ± 1.2
(b) White blood cell count and analysis
  WBC LYM LYM MON MON NEU NEU EOS EOS BAS BAS
(× 109/L) (× 109/L) (%) (× 109/L) (%) (× 109/L) (%) (× 109/L) (%) (× 109/L) (%)
NP 3.8 ± 0.8 3.2 ± 0.6 86.3 ± 6.1 0,1 ± 0.04 1.7 ± 1.2 0.2 ± 0.1 3.6 ± 2.2 0 ± 0 0 ± 0 0.3 ± 0.2 8.7 ± 4.3
A30E 6.3 ± 2.2* 4.6 ± 1.9 79.5 ± 5.7 0.1 ± 0.06 1.7 ± 0.8 0.2 ± 0.06 2.9 ± 0.3 0 ± 0.02 0.2 ± 0.4 1 ± 0.7* 14.4 ± 5.3*
A30L 8.6 ± 1.9* 6.5 ± 1.6* 78.1 ± 6.4 0.2 ± 0.1 2.3 ± 0.9 0.5 ± 0.1* 6.3 ± 1.4* 0.1 ± 0.1 1.1 ± 1.2 1.1 ± 0.4* 13.1 ± 6*
(c) Platelet analysis
  PLT (× 109/L) RDW-CV (%) PDW (%) MPV (fL) P-LCR (%) PCT (%)
NP 583.6 ± 294.3 21.7 ± 1.2 8 ± 1.7 7.4 ± 0.7 9.6 ± 5.2 0.5 ± 0.2
A30E 804.6 ± 127.3* 22.6 ± 2.1 7.5 ± 0.4 7.1 ± 0.3 6.6 ± 1.2* 0.6 ± 0.1
A30L 476.4 ± 293.5 21.3 ± 1.1 8.8 ± 0.7 8 ± 0.4 10.6 ± 2.7 0.4 ± 0.2
  1. (a) Red blood cell count and analysis. RBC red blood cell count, HGB hemoglobin, HCT red blood cell specific volume, MCV mean cell volume, MCH mean corpsular hemoglobin, MCHC mean corpuscular hemoglobin concentration, RDW red blood Cell distribution width. (b) White blood cell count and analysis. The percentage (%) and absolute number (#) of white blood cells were shown. WBC white blood cell count, LYM lymphocytem, MON moncyte, NEU neutrophil, BAS basicyte, EOS eosinophil. (c) Platelet analysis. PLT platelet count, PDW platelet volume distribution width, MPV mean platelet volume, P-LCR proportion of large platelets, PCT thrombocytocrit. *p < 0.05 compared with NP group by ANOVA with Tukey’s test post-hoc. n = 7–10 per group