TY - JOUR AU - Aoshiba, K. AU - Tsuji, T. AU - Kameyama, S. AU - Itoh, M. AU - Semba, S. AU - Yamaguchi, K. PY - 2013 DA - 2013// TI - Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury JO - Exp Toxicol Pathol VL - 65 UR - https://doi.org/10.1016/j.etp.2013.04.001 DO - 10.1016/j.etp.2013.04.001 ID - Aoshiba2013 ER - TY - JOUR AU - Aoshiba, K. AU - Tsuji, T. AU - Nagai, A. PY - 2003 DA - 2003// TI - Bleomycin induces cellular senescence in alveolar epithelial cells JO - Eur Respir J VL - 22 UR - https://doi.org/10.1183/09031936.03.00011903 DO - 10.1183/09031936.03.00011903 ID - Aoshiba2003 ER - TY - STD TI - Berridge MJ. Vitamin D, reactive oxygen species and calcium signalling in ageing and disease. Philos Trans R Soc Lond B Biol Sci. 2016;371(1700). ID - ref3 ER - TY - JOUR AU - Bolzan, A. D. AU - Bianchi, M. S. PY - 2018 DA - 2018// TI - DNA and chromosome damage induced by bleomycin in mammalian cells: an update JO - Mutat Res VL - 775 UR - https://doi.org/10.1016/j.mrrev.2018.02.003 DO - 10.1016/j.mrrev.2018.02.003 ID - Bolzan2018 ER - TY - JOUR AU - Chilosi, M. AU - Carloni, A. AU - Rossi, A. AU - Poletti, V. PY - 2013 DA - 2013// TI - Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema JO - Transl Res VL - 162 UR - https://doi.org/10.1016/j.trsl.2013.06.004 DO - 10.1016/j.trsl.2013.06.004 ID - Chilosi2013 ER - TY - JOUR AU - Chua, F. AU - Gauldie, J. AU - Laurent, G. J. PY - 2005 DA - 2005// TI - Pulmonary fibrosis: searching for model answers JO - Am J Respir Cell Mol Biol VL - 33 UR - https://doi.org/10.1165/rcmb.2005-0062TR DO - 10.1165/rcmb.2005-0062TR ID - Chua2005 ER - TY - STD TI - Chung M, Balk EM, Brendel M, Ip S, Lau J, Lee J, et al. Vitamin D and calcium: a systematic review of health outcomes. Evid Rep Technol Assess (Full Rep). 2009;(183):1–420. ID - ref7 ER - TY - JOUR AU - Datta Mitra, A. AU - Raychaudhuri, S. P. AU - Abria, C. J. AU - Mitra, A. AU - Wright, R. AU - Ray, R. PY - 2013 DA - 2013// TI - 1alpha,25-Dihydroxyvitamin-D3-3-bromoacetate regulates AKT/mTOR signaling cascades: a therapeutic agent for psoriasis JO - J Invest Dermatol VL - 133 UR - https://doi.org/10.1038/jid.2013.3 DO - 10.1038/jid.2013.3 ID - Datta Mitra2013 ER - TY - STD TI - Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci. 1995; 92(20):9363-67. ID - ref9 ER - TY - JOUR AU - Ding, N. AU - Yu, R. T. AU - Subramaniam, N. AU - Sherman, M. H. AU - Wilson, C. AU - Rao, R. PY - 2013 DA - 2013// TI - A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response JO - Cell VL - 153 UR - https://doi.org/10.1016/j.cell.2013.03.028 DO - 10.1016/j.cell.2013.03.028 ID - Ding2013 ER - TY - JOUR AU - Finklea, J. D. AU - Grossmann, R. E. AU - Tangpricha, V. PY - 2011 DA - 2011// TI - Vitamin D and chronic lung disease: a review of molecular mechanisms and clinical studies JO - Adv Nutr VL - 2 UR - https://doi.org/10.3945/an.111.000398 DO - 10.3945/an.111.000398 ID - Finklea2011 ER - TY - JOUR AU - Forli, L. AU - Halse, J. AU - Haug, E. AU - Bjortuft, O. AU - Vatn, M. AU - Kofstad, J. PY - 2004 DA - 2004// TI - Vitamin D deficiency, bone mineral density and weight in patients with advanced pulmonary disease JO - J Intern Med VL - 256 UR - https://doi.org/10.1111/j.1365-2796.2004.01337.x DO - 10.1111/j.1365-2796.2004.01337.x ID - Forli2004 ER - TY - JOUR AU - Haring, M. AU - Offermann, S. AU - Danker, T. AU - Horst, I. AU - Peterhansel, C. AU - Stam, M. PY - 2007 DA - 2007// TI - Chromatin immunoprecipitation: optimization, quantitative analysis and data normalization JO - Plant Methods VL - 3 UR - https://doi.org/10.1186/1746-4811-3-11 DO - 10.1186/1746-4811-3-11 ID - Haring2007 ER - TY - JOUR AU - Hecker, L. AU - Logsdon, N. J. AU - Kurundkar, D. AU - Kurundkar, A. AU - Bernard, K. AU - Hock, T. PY - 2014 DA - 2014// TI - Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance JO - Sci Transl Med VL - 6 UR - https://doi.org/10.1126/scitranslmed.3008182 DO - 10.1126/scitranslmed.3008182 ID - Hecker2014 ER - TY - JOUR AU - Ito, I. AU - Waku, T. AU - Aoki, M. AU - Abe, R. AU - Nagai, Y. AU - Watanabe, T. PY - 2013 DA - 2013// TI - A nonclassical vitamin D receptor pathway suppresses renal fibrosis JO - J Clin Invest VL - 123 UR - https://doi.org/10.1172/JCI67804 DO - 10.1172/JCI67804 ID - Ito2013 ER - TY - JOUR AU - Ito, T. AU - Teo, Y. V. AU - Evans, S. A. AU - Neretti, N. AU - Sedivy, J. M. PY - 2018 DA - 2018// TI - Regulation of cellular senescence by Polycomb chromatin modifiers through distinct DNA damage- and histone methylation-dependent pathways JO - Cell Rep VL - 22 UR - https://doi.org/10.1016/j.celrep.2018.03.002 DO - 10.1016/j.celrep.2018.03.002 ID - Ito2018 ER - TY - JOUR AU - Jacobs, J. J. AU - Kieboom, K. AU - Marino, S. AU - DePinho, R. A. AU - Lohuizen, M. PY - 1999 DA - 1999// TI - The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus JO - Nature VL - 397 UR - https://doi.org/10.1038/16476 DO - 10.1038/16476 ID - Jacobs1999 ER - TY - JOUR AU - Jain, S. K. AU - Micinski, D. PY - 2013 DA - 2013// TI - Vitamin D upregulates glutamate cysteine ligase and glutathione reductase, and GSH formation, and decreases ROS and MCP-1 and IL-8 secretion in high-glucose exposed U937 monocytes JO - Biochem Biophys Res Commun VL - 437 UR - https://doi.org/10.1016/j.bbrc.2013.06.004 DO - 10.1016/j.bbrc.2013.06.004 ID - Jain2013 ER - TY - JOUR AU - Kawanami, O. AU - Ferrans, V. J. AU - Crystal, R. G. PY - 1982 DA - 1982// TI - Structure of alveolar epithelial cells in patients with fibrotic lung disorders JO - Lab Investig VL - 46 ID - Kawanami1982 ER - TY - JOUR AU - King, T. E. AU - Pardo, A. AU - Selman, M. PY - 2011 DA - 2011// TI - Idiopathic pulmonary fibrosis JO - Lancet VL - 378 UR - https://doi.org/10.1016/S0140-6736(11)60052-4 DO - 10.1016/S0140-6736(11)60052-4 ID - King2011 ER - TY - JOUR AU - Kuwano, K. AU - Araya, J. AU - Hara, H. AU - Minagawa, S. AU - Takasaka, N. AU - Ito, S. PY - 2016 DA - 2016// TI - Cellular senescence and autophagy in the pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) JO - Respir Investig VL - 54 UR - https://doi.org/10.1016/j.resinv.2016.03.010 DO - 10.1016/j.resinv.2016.03.010 ID - Kuwano2016 ER - TY - JOUR AU - Kuwano, K. AU - Kunitake, R. AU - Kawasaki, M. AU - Nomoto, Y. AU - Hagimoto, N. AU - Nakanishi, Y. PY - 1996 DA - 1996// TI - P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis JO - Am J Respir Crit Care Med VL - 154 UR - https://doi.org/10.1164/ajrccm.154.2.8756825 DO - 10.1164/ajrccm.154.2.8756825 ID - Kuwano1996 ER - TY - JOUR AU - Lagares, D. AU - Busnadiego, O. AU - Garcia-Fernandez, R. A. AU - Kapoor, M. AU - Liu, S. AU - Carter, D. E. PY - 2012 DA - 2012// TI - Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation JO - Arthritis Rheum VL - 64 UR - https://doi.org/10.1002/art.33482 DO - 10.1002/art.33482 ID - Lagares2012 ER - TY - JOUR AU - Lee, Y. C. AU - Hung, S. Y. AU - Liou, H. H. AU - Lin, T. M. AU - Tsai, C. H. AU - Lin, S. H. PY - 2015 DA - 2015// TI - Vitamin D can ameliorate chlorhexidine gluconate-induced peritoneal fibrosis and functional deterioration through the inhibition of epithelial-to-mesenchymal transition of mesothelial cells JO - Biomed Res Int VL - 2015 ID - Lee2015 ER - TY - JOUR AU - Lv, X. X. AU - Wang, X. X. AU - Li, K. AU - Wang, Z. Y. AU - Li, Z. AU - Lv, Q. PY - 2013 DA - 2013// TI - Rupatadine protects against pulmonary fibrosis by attenuating PAF-mediated senescence in rodents JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0068631 DO - 10.1371/journal.pone.0068631 ID - Lv2013 ER - TY - STD TI - Magro-Lopez E, Guijarro T, Martinez I, Martin-Vicente M, Liste I, Zambrano A. A two-dimensional human minilung system (Model) for respiratory syncytial virus infections. Viruses. 2017;9(12):379. ID - ref26 ER - TY - STD TI - Manson JE, Cook NR, Lee IM, Christen W, Bassuk SS, Mora S, et al. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease. N Engl J Med. 2018. https://doi.org/10.1056/NEJMoa1809944. ID - ref27 ER - TY - JOUR AU - Mascitelli, L. AU - Pezzetta, F. AU - Goldstein, M. R. PY - 2010 DA - 2010// TI - Vitamin D and mortality from pulmonary fibrosis JO - Chest VL - 137 UR - https://doi.org/10.1378/chest.09-1646 DO - 10.1378/chest.09-1646 ID - Mascitelli2010 ER - TY - JOUR AU - Meredith, A. AU - Boroomand, S. AU - Carthy, J. AU - Luo, Z. AU - McManus, B. PY - 2015 DA - 2015// TI - 1,25 Dihydroxyvitamin D3 inhibits TGFbeta1-mediated primary human cardiac Myofibroblast activation JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0128655 DO - 10.1371/journal.pone.0128655 ID - Meredith2015 ER - TY - JOUR AU - Moeller, A. AU - Ask, K. AU - Warburton, D. AU - Gauldie, J. AU - Kolb, M. PY - 2008 DA - 2008// TI - The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? JO - Int J Biochem Cell Biol VL - 40 UR - https://doi.org/10.1016/j.biocel.2007.08.011 DO - 10.1016/j.biocel.2007.08.011 ID - Moeller2008 ER - TY - STD TI - Newberry SJ, Chung M, Shekelle PG, Booth MS, Liu JL, Maher AR, et al. Vitamin D and Calcium: A Systematic Review of Health Outcomes (Update). Evid Rep Technol Assess (Full Rep). 2014;(217):1–929. ID - ref31 ER - TY - JOUR AU - Noble, P. W. PY - 2008 DA - 2008// TI - Epithelial fibroblast triggering and interactions in pulmonary fibrosis JO - Eur Respir Rev VL - 17 UR - https://doi.org/10.1183/09059180.00010904 DO - 10.1183/09059180.00010904 ID - Noble2008 ER - TY - JOUR AU - Pike, J. W. AU - Christakos, S. PY - 2017 DA - 2017// TI - Biology and mechanisms of action of the Vitamin D hormone JO - Endocrinol Metab Clin N Am VL - 46 UR - https://doi.org/10.1016/j.ecl.2017.07.001 DO - 10.1016/j.ecl.2017.07.001 ID - Pike2017 ER - TY - JOUR AU - Schafer, M. J. AU - White, T. A. AU - Iijima, K. AU - Haak, A. J. AU - Ligresti, G. AU - Atkinson, E. J. PY - 2017 DA - 2017// TI - Cellular senescence mediates fibrotic pulmonary disease JO - Nat Commun VL - 8 UR - https://doi.org/10.1038/ncomms14532 DO - 10.1038/ncomms14532 ID - Schafer2017 ER - TY - JOUR AU - Schapochnik, A. AU - Silva, M. R. AU - Leal, M. P. AU - Esteves, J. AU - Hebeda, C. B. AU - Sandri, S. PY - 2018 DA - 2018// TI - Vitamin D treatment abrogates the inflammatory response in paraquat-induced lung fibrosis JO - Toxicol Appl Pharmacol VL - 355 UR - https://doi.org/10.1016/j.taap.2018.06.020 DO - 10.1016/j.taap.2018.06.020 ID - Schapochnik2018 ER - TY - JOUR AU - Sedelnikova, O. A. AU - Horikawa, I. AU - Zimonjic, D. B. AU - Popescu, N. C. AU - Bonner, W. M. AU - Barrett, J. C. PY - 2004 DA - 2004// TI - Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks JO - Nat Cell Biol VL - 6 UR - https://doi.org/10.1038/ncb1095 DO - 10.1038/ncb1095 ID - Sedelnikova2004 ER - TY - JOUR AU - Selman, M. AU - Pardo, A. PY - 2006 DA - 2006// TI - Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers JO - Proc Am Thorac Soc VL - 3 UR - https://doi.org/10.1513/pats.200601-003TK DO - 10.1513/pats.200601-003TK ID - Selman2006 ER - TY - JOUR AU - Shivshankar, P. AU - Brampton, C. AU - Miyasato, S. AU - Kasper, M. AU - Thannickal, V. J. AU - Saux, C. J. PY - 2012 DA - 2012// TI - Caveolin-1 deficiency protects from pulmonary fibrosis by modulating epithelial cell senescence in mice JO - Am J Respir Cell Mol Biol VL - 47 UR - https://doi.org/10.1165/rcmb.2011-0349OC DO - 10.1165/rcmb.2011-0349OC ID - Shivshankar2012 ER - TY - JOUR AU - Tan, Z. X. AU - Chen, Y. H. AU - Xu, S. AU - Qin, H. Y. AU - Zhang, C. AU - Zhao, H. PY - 2016 DA - 2016// TI - Calcitriol inhibits bleomycin-induced early pulmonary inflammatory response and epithelial-mesenchymal transition in mice JO - Toxicol Lett VL - 240 UR - https://doi.org/10.1016/j.toxlet.2015.10.022 DO - 10.1016/j.toxlet.2015.10.022 ID - Tan2016 ER - TY - JOUR AU - Valcheva, P. AU - Cardus, A. AU - Panizo, S. AU - Parisi, E. AU - Bozic, M. AU - Lopez Novoa, J. M. PY - 2014 DA - 2014// TI - Lack of vitamin D receptor causes stress-induced premature senescence in vascular smooth muscle cells through enhanced local angiotensin-II signals JO - Atherosclerosis VL - 235 UR - https://doi.org/10.1016/j.atherosclerosis.2014.05.911 DO - 10.1016/j.atherosclerosis.2014.05.911 ID - Valcheva2014 ER - TY - JOUR AU - Wang, Z. AU - Zhang, H. AU - Sun, X. AU - Ren, L. PY - 2016 DA - 2016// TI - The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-beta/Smad signaling and activation of the Nrf2/HO-1 pathway JO - Mol Med Rep VL - 14 UR - https://doi.org/10.3892/mmr.2016.5563 DO - 10.3892/mmr.2016.5563 ID - Wang2016 ER - TY - JOUR AU - Yanagi, S. AU - Tsubouchi, H. AU - Miura, A. AU - Matsumoto, N. AU - Nakazato, M. PY - 2015 DA - 2015// TI - Breakdown of epithelial barrier integrity and overdrive activation of alveolar epithelial cells in the pathogenesis of acute respiratory distress syndrome and lung fibrosis JO - Biomed Res Int VL - 2015 UR - https://doi.org/10.1155/2015/573210 DO - 10.1155/2015/573210 ID - Yanagi2015 ER - TY - JOUR AU - Zambrano, A. AU - Garcia-Carpizo, V. AU - Gallardo, M. E. AU - Villamuera, R. AU - Gomez-Ferreria, M. A. AU - Pascual, A. PY - 2014 DA - 2014// TI - The thyroid hormone receptor beta induces DNA damage and premature senescence JO - J Cell Biol VL - 204 UR - https://doi.org/10.1083/jcb.201305084 DO - 10.1083/jcb.201305084 ID - Zambrano2014 ER - TY - JOUR AU - Zhang, Z. AU - Yu, X. AU - Fang, X. AU - Liang, A. AU - Yu, Z. AU - Gu, P. PY - 2015 DA - 2015// TI - Preventive effects of vitamin D treatment on bleomycin-induced pulmonary fibrosis JO - Sci Rep VL - 5 UR - https://doi.org/10.1038/srep17638 DO - 10.1038/srep17638 ID - Zhang2015 ER - TY - JOUR AU - Zhang, Z. M. AU - Gu, P. AU - Yi, X. H. AU - Fang, X. AU - Zeng, Y. AU - Zhang, S. X. PY - 2013 DA - 2013// TI - Effects of 1, 25 (OH)2D3 on bleomycin-induced pulmonary fibrosis in mice JO - Zhonghua Jie He He Hu Xi Za Zhi VL - 36 ID - Zhang2013 ER -