Fig. 2
From: aThe characteristics of glucose metabolism in the sulfonylurea receptor 1 knockout rat model
Expression and colocalization of insulin and glucagon in SUR1−/− and wild-type rats. Immunofluorescent colocalization of insulin and glucagon in SUR1−/− male rats (a), SUR1−/− female rats (b), wild-type male rats (c) and wild-type female rats (d). Pancreatic sections were immunostained with anti-insulin antibody (green) and anti-glucagon antibody (red). SUR1−/− rats showed obviously reduced insulin expression with unchanged glucagon expression compared to wild-type rats. (A) Immunofluorescent staining for glucagon and insulin. (B) Quantitative analysis of glucagon expression. (C) Quantitative analysis of insulin expression. The values denote the means ± SEM. *: P < 0.05. Original magnification, × 400