Fig. 7
From: Loss of intestinal sympathetic innervation elicits an innate immune driven colitis
Hypothesized model. Schematic overview of the colon before and after sympathetic denervation. In Rag1−/− mice after sympathectomy, there are more immature monocytes (‘Mo’, in red) compared to mature macrophages (‘Mϕ’, in blue), there is goblet cell depletion and levels of pro-inflammatory cytokines are higher compared to the sham group