Table 3 Histology score adapted from Read et al. (2001)
From: Loss of intestinal sympathetic innervation elicits an innate immune driven colitis
| Score | 0 | 1 | 2 | 3 | 4 |
|---|---|---|---|---|---|
| Mono- and polymorphonuclear infiltrate | Normal | Increase in mucosa | Increase in mucosa and submucosa | Extending into mucosa, submucosa, tunica muscularis and/or serosa | |
| Goblet cells | Normal, large amount | Depletion of < 10% | Depletion of 10–50% | Depletion of > 50% | |
| Crypt loss | No crypt loss | < 10% crypt loss | 10–50% crypt loss | > 50% crypt loss | |
| Epithelial hyperplasia | Normal | Slight hyperplasia | 2-3x increase of crypt length | >3x increase of crypt length | |
| Ulcerations | No ulceration | Ulcerations | |||
| Crypt abscesses | No abscesses | Crypt abscesses |