Table 2 The effect of PVT1 knockdown on cardiac function and hemodynamics in mice (mean ± s)

Number

8

8

8

8

LVDd (mm)

3.58 ± 0.49

5.11 ± 0.86*

5.16 ± 0.76

4.05 ± 0.62^#

LVDs (mm)

2.38 ± 0.46

4.77 ± 0.54*

4.64 ± 0.43

3.35 ± 0.84^#

IVSd (mm)

0.63 ± 0.04

0.82 ± 0.03*

0.81 ± 0.04

0.71 ± 0.01^#

IVSs (mm)

1.08 ± 0.02

1.23 ± 0.03*

1.22 ± 0.02

1.14 ± 0.02^#

LVEF (%)

80.95 ± 2.15

51.23 ± 3.44*

52.04 ± 3.06

71.81 ± 2.95^#

LVFS (%)

41.26 ± 3.68

25.75 ± 3.91*

25.48 ± 3.88

35.28 ± 3.84^#