|
OR (95% CI)
|
p
|
Per-SD increase
|
p
|
---|
Unadjusted
|
2.2 (1.3, 3.7)
|
0.003
|
1.4 (1.1, 1.8)
|
0.001
|
Adjusted model 1
|
2.1 (1.2, 3.6)
|
0.012
|
1.4 (1.1, 1.8)
|
0.004
|
Adjusted model 2
|
1.9 (1.1, 3.4)
|
0.032
|
1.4 (1.1, 1.7)
|
0.018
|
- Model 1: adjusted for age, sex, BMI, current smoking, LDL-C, AF, DM and hypertension; model 2: adjusted for model 1 plus NT-proBNP levels, eGFR, and medications (including ACEIs/ARBs, beta-blockers)
- Abbreviations: 2OG 2-Oxoglutarate, BMI body mass index, LDL-C low-density lipoprotein cholesterol, AF Atrial fibrillation, DM Diabetes mellitus, NT-proBNP N-terminal pro B-type natriuretic peptide, eGFR estimated glomerular filtration rate, ACEIs/ARBs angiotensin-converting enzyme inhibitors/angiotensin receptor blockers