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Fig. 4 | Molecular Medicine

Fig. 4

From: PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma

Fig. 4

PGK1 knockdown inhibits phosphorylation of JNK, ERK, and AKT pathway. a. Western blot was performed to evaluate the effects of PGK1 knockdown on phosphorylation levels of JNK, ERK, and AKT in Ishikawa cancer cell line. β-actin was used as a loading control. b. Semi-quantitative analysis of protein level in A. c. Western blot was performed to evaluate the effects of PGK1 knockdown on phosphorylation levels of JNK, ERK, and AKT pathway in HEC1A cancer cell line. β-actin was used as a loading control. d. Semi-quantitative analysis of protein level in C. Data were shown as mean ± SD based on three independent experiments. *, P < 0.05, **, P < 0.01 compared with shNC group

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Molecular Medicine

ISSN: 1528-3658