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Fig. 5 | Molecular Medicine

Fig. 5

From: HDAC6 is associated with the formation of aortic dissection in human

Fig. 5

The signaling pathways evaluated in human aorta samples. The phosphorylation and total protein levels of key molecules in signaling pathways were detected by western blot in the aorta of CAD and TAAD patients. a The phosphorylation and total protein levels of mTOR, AKT and AMPKα; (b) The phosphorylation, non-phosphorylation and total protein levels of β-catenin; (c) The phosphorylation and total protein levels of MEK1/2, ERK1/2, JNK1/2, and P38; (d) The phosphorylation and total protein levels of IKKβ, NF-κB-p65, Smad1/5, Smad2, and Smad3. n = 6 pooled samples per group, *p < 0.05 vs. CAD

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