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Table 1 The clinic information of patients

From: HDAC6 is associated with the formation of aortic dissection in human

Clinical Indicators

CAD

TAAD

Sex (Male/Female)

27/9

27/9

Age (year)

60.3 ± 5.1

53.8 ± 8.0**

BMI (kg/m2)

23.4 ± 2.9

23.4 ± 1.9

Smokers (n, %)

18 (50.0%)

19 (52.7%)

Diabetes (n, %)

14 (38.9%)

0 (0.0%)**

Hypertension (n, %)

24 (66.7%)

25 (69.4%)

NYHA classification

2.4 ± 1.0

2.2 ± 0.8

SBP (mmHg)

125.7 ± 17.7

134.0 ± 29.8

Aortic Diameter (mm)

32.2 ± 3.3

41.6 ± 7.7**

EF (%)

53.9 ± 14.1

60.2 ± 4.2*

WBC (109/L)

7.6 ± 3.9

11.5 ± 4.3**

hs-TnI (μg/L)

21.4 (10.0, 171.0)

66.8 (9.6, 528.8)

pro-BNP (pg/mL)

677.5 (222, 2285)

450 (274, 891)

D-dimer (μg/L)

NA

22.1 ± 13.3

  1. CAD Coronary artery disease, TAAD Type A aortic dissection, BMI Body mass index, SBP Systolic blood pressure, NYHA classification New York Heart Association classification, EF Ejection fraction, WBC White blood cell. Aortic diameter means the diameter of ascending aorta except when patients with aneurysm of descending aorta that means the diameter of descending aorta, NA Not available. *Indicates significant changes from TAAD compared with CAD, *p < 0.05; **p < 0.01