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Fig. 1 | Molecular Medicine

Fig. 1

From: Tag-based next generation sequencing: a feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients

Fig. 1

EGFR mutations in 42 post-TKI NSCLC patients. (a) Distribution of the various EGFR mutations types in the 42 patients according to Real Time PCR (PCR) and tag-based NGS (NGS). The y-axis shows patients count according to different mutation patterns detected by the two platforms. (b) Coincident Rate between Real Time PCR (grey bars) and tag-based NGS (black bars) according to the different EGFR mutations types found. The y-axis indicated the number of cases concordant for the specific variation with both Real Time PCR and tag-based NGS and corresponding percentages are indicated within the histogram. PCR, Real Time PCR; NGS, tag-based NGS; del, deletions; Sens, sensitizing; pos, positive; neg, negative

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