Patient N.
|
EGFR mutation in post-TKI Plasma
|
EGFR mutation in post-TKI Tissues
|
Tissue obtained by
|
Tumor source
|
---|
Sensitizing
|
T790M
|
Sensitizing
|
T790M
|
---|
2
|
exon 19 del
|
pos
|
exon 19 del
|
pos
|
needle biopsy
|
pleura
|
18
|
exon 19 del
|
pos
|
exon 19 del
|
pos
|
cytology
|
lymph node
|
34
|
exon 19 del
|
pos
|
exon 19 del
|
pos
|
needle biopsy
|
lung
|
37
|
exon 19 del
|
pos
|
exon 19 del
|
pos
|
needle biopsy
|
bronchus
|
14
|
exon 19 del
|
neg
a
|
exon 19 del
|
pos
|
cytology
|
pleural fluid
|
11
|
L858R
|
neg
|
L858R
|
neg
|
cytology
|
lymph node
|
4
|
neg
|
neg
|
L858R
|
neg
|
cytology
|
liquor
|
13
|
L858R
|
neg
|
L858R
|
neg
|
cytology
|
pleural fluid
|
25
|
L858R
|
pos
|
L858R
|
neg
|
needle biopsy
|
lung
|
28
|
exon 20 ins
|
neg
|
exon 20 ins
|
neg
|
needle biopsy
|
lymph node
|
8
|
L858R
|
neg
|
L858R
|
neg
|
cytology
|
lymph node
|
20
|
L858R
|
neg
|
L858R
|
neg
|
cytology
|
bronchus/trachea
|
39
|
G719C/S768I
|
pos
|
G719C/S768I
|
neg
|
biopsy
|
bronchus
|
42
|
exon 19 del
|
neg
|
exon 19 del
|
neg
|
cytology
|
vertebral bone
|
40
|
exon 19 del
|
neg
|
exon 19 del
|
neg
|
needle biopsy
|
lung
|
- del deletion, ins insertion, pos positive, neg negative
- adiscordant EGFR results between plasma and tissues are indicated in bold letters