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Table 1 Clinical characteristics of AMI patients and the control subjects

From: Circulating miR-26a-1, miR-146a and miR-199a-1 are potential candidate biomarkers for acute myocardial infarction

Variable

AMI group (n = 31)

Control group (n = 27)

p-value

Male/Female (n/n)1

25/6

19/8

0.362

Age (years)2

61.1 ± 10.0

60.1 ± 12.2

0.379

BMI (kg/m2)2

25.5 ± 2.1

24.8 ± 4.1

0.368

Smoking status

 Current smoker (%)1

58.1%

44.4%

0.188

 Former smoker (%)1

9.7%

0

0.370

 Never (%)1

32.2%

55.6%

0.074

Hypertension (%)1

71.0%

22.2%

< 0.001**

Diabetes (%)1

32.3%

11.1%

0.054

SBP (mmHg)3

129.4 ± 22.0

124.6 ± 11.9

0.258

DBP (mmHg)3

78.8 ± 12.8

71.9 ± 7.5

0.017*

Heart rate (beats/minutes)3

73.3 ± 12.2

77.3 ± 9.3

0.052

Killip class at admission ≥ II (%)1

32.3

0

0.001**

Blood glucose (mmol/L)3

6.7 ± 2.9

5.4 ± 2.0

0.720

Total cholesterol (mmol/L)3

4.7 ± 1.0

4.2 ± 1.5

0.119

Triglycerides (mmol/L)3

2.3 ± 3.0

1.1 ± 0.6

0.002**

HDL (mmol/L)3

1.1 ± 0.3

1.2 ± 0.5

0.307

LDL (mmol/L)3

2.7 ± 0.8

2.5 ± 1.1

0.293

WBC (× 109/L)3

9.2 ± 3.0

7.7 ± 3.2

0.067

Cr (μmol/L)3

63.4 ± 14.0

70.0 ± 23.1

0.176

NT-proBNP (pg/ml)3

1497.5 ± 1667.4

77.2 ± 86.8

0.001**

CK-MB (U/L)3

47.5 ± 72.1

12.1 ± 8.9

< 0.001**

MYO (μg/L)3

55.4 ± 22.8

35.4 ± 10.7

0.250

Hs-cTNT (μg/L)3

2.08 ± 2.11

0.002 ± 0.000

< 0.001**

Concurrent medications

 ACE inhibitors (%)1

80.6%

0

< 0.001**

 Beta-blockers (%)1

96.8%

0

< 0.001**

 Nitrates (%)1

96.8%

3.7%

< 0.001**

 Statins (%)1

100.0%

0

< 0.001**

 Aspirins (%)1

100.0%

0

< 0.001**

 Colpidogrel (%)1

41.9%

0

< 0.001**

  1. BMI Body mass index, DM Diabetes mellitus, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG total triglycerides, HDL high-density lipoprotein, LDL low-density lipoprotein, WBC white blood cell, Cr creatinine, CK-MB Creatine Kinase-MB, Hs-TNT troponin T. Data are shown as the mean ± SD; 1Chi-square tests for the differences in the distribution frequencies between AMI patients and controls; 2Student’s t test for the differences between the AMI and control groups; 3Mann-Whitney U test for the differences between the AMI and control groups