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Fig. 3 | Molecular Medicine

Fig. 3

From: Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195

Fig. 3

APS reversed the oxidative stress and mitochondrial damage in RPE cells induced by HG. a Treatment with APS significantly decreased the MDA and increased SOD level which were induced by HG or HG + NG treatment in ARPE-19 cells. b Treatment with APS significantly decreased the MDA and increased SOD level which were induced by HG or HG + NG treatment in PRPE cells. c Western blotting showed treatment with APS significantly increased the ratio of mitochondrial to cytosol cyt-c which induced by HG and HG + NG treatment in ARPE-19 and PRPE cells. d The statistical results of western blotting. Error bars represented mean ± SD. *** p < 0.001, ** p < 0.01, * p < 0.05

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Molecular Medicine

ISSN: 1528-3658