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Fig. 4 | Molecular Medicine

Fig. 4

From: Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195

Fig. 4

APS ameliorated the mitochondrial membrane potential induced by HG in RPE cells. a Immunostaining showed treatment with APS significantly decreased the ratio of monomeric to aggregate JC-1 which was induced by HG or HG + NG treatment in ARPE-19 cells. b. Immunostaining showed treatment with APS significantly decreased the ratio of monomeric to aggregate JC-1 which was induced by HG or HG + NG treatment in PRPE. c The statistical results of the staining in A and B. Error bars represented mean ± SD. *** p < 0.001, ** p < 0.01, * p < 0.05

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