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Fig. 9 | Molecular Medicine

Fig. 9

From: Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195

Fig. 9

MiR-195 activated mitochondrial apoptotic pathway in ARPE-19 cells. a Western blotting showed miR-195 mimics significantly increased the expressions of Bax, cleaved caspase-9, cleaved caspase-3 and cleaved PARP while decreased the expressions of Bcl-2 and uncleaved form of caspase-9, caspase-3 and PARP compared to the APS treated ARPE-19 cells. bThe statistical results of western blotting in A. Error bars represented mean ± SD. *** p < 0.001, ** p < 0.01, * p < 0.05

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