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Fig. 1 | Molecular Medicine

Fig. 1

From: CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer

Fig. 1

Pro-apoptotic activity in cervical cancer cells (CaSki, HeLa and SiHa) following CKD-602 treatment. Cells were incubated with CKD602 in a dose-dependent manner (0 [control], ½ IC50, IC50 ng/ml each cells) for 48 h. a. The percentage of apoptosic cells was evaluated using flow cytometic analysis with Annexin V and PI staining. b. The percentage of apoptosic cells measured by flow cytometry. Results are expressed as the mean ± SEM (*p < 0.05 and **p < 0.01). c. Western blot analysis of apoptosis-related proteins in cervical cancer cells

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Molecular Medicine

ISSN: 1528-3658