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Table 1 Seven candidate risk variants for LOAD

From: A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease

Position (hg19) Gene Ref./Alt. Protein dbSNP ID No. of carriers/No. determined
LOAD NC
12:120651694 PXN T/C p.Tyr487Cys rs980452538 0/2176 0/909
8:145154709 SHARPIN C/T p.Gly186Arg rs572750141 9/2172 0/916
8:145154228 SHARPIN C/T p.Gly292Arg rs774802799 0/2183 0/917
19:10477232 TYK2 C/T p.Val164Met rs531355933 3/2181 0/916
7:148769094 ZNF786 C/T p.Arg257His rs771874615 0/2179 0/914
7:148767975 ZNF786 T/C p.Tyr630Cys rs762922242 0/2180 0/915
7:148767897 ZNF786 C/T p.Gly656Asp NA 0/2175 0/914
  1. NA; Not available