Fig. 2

Effects of Fimasartan on CD4⁺ T cells, Treg cells, and anti-inflammatory cytokines in the peripheral blood of ApoE KO mice. a Immunohistochemical images showing the expression of CD4 (brown) at 28 days after CA injury and/or fimasartan administration. Scale bar: 100 μm. b Representative pictures showing that CD4⁺ T cell subsets were gated using flow cytometry. The numbers indicate positive percentages of CD4⁺ T cells. c Results of statistical analyses of Treg cells in peripheral blood at 28 days after CA injury and/or fimasartan administration. d Plasma levels of Treg-related cytokines, including IL-10 and TGFβ were measured by ELISA. All experimental data are from n = 12 of ApoE KO mice in each group. The values are presented as the mean ± SD. *p < 0.05. NS, not significant