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Fig. 3 | Molecular Medicine

Fig. 3

From: FBXW7 suppresses HMGB1-mediated innate immune signaling to attenuate hepatic inflammation and insulin resistance in a mouse model of nonalcoholic fatty liver disease

Fig. 3

FBXW7 attenuates inflammatory response in HFD-fed mouse livers. a Representative confocal immunofluorescence images of F4/80 (red) and DAPI (blue) in mouse livers (n = 4). b The mRNA level of inflammation-related genes in mouse livers (n = 3). c Immunoblotting and densitometry of nuclear and cytoplasmic NF-κB p65 in mouse livers (n = 4). All of the values are expressed as the mean ± SD. *P < 0.05, ***P < 0.001 versus the ND + Ad-GFP group; #P < 0.05, ##P < 0.01, ###P < 0.001 versus the HFD + Ad-GFP group

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Molecular Medicine

ISSN: 1528-3658