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Fig. 5 | Molecular Medicine

Fig. 5

From: FBXW7 suppresses HMGB1-mediated innate immune signaling to attenuate hepatic inflammation and insulin resistance in a mouse model of nonalcoholic fatty liver disease

Fig. 5

FBXW7 abates PKR signaling in HFD-fed mouse livers. a and (b) Immunoblotting and densitometry of the components of PKR signaling in mouse livers (n = 4). *P < 0.05, **P < 0.01, ***P < 0.001 versus the ND + Ad-GFP group; #P < 0.05, ##P < 0.01, ###P < 0.001 versus the HFD + Ad-GFP group; &P < 0.05, &&P < 0.01, versus the HFD + shScramble group

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Molecular Medicine

ISSN: 1528-3658