Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Dystrophin R16/17 protein therapy restores sarcolemmal nNOS in trans and improves muscle perfusion and function

Fig. 5

R16/17.GFP.Pal protein transfer improves muscle function of ΔR4 mice. ΔR4 mice injected with R16/17 protein were subjected to long-term treadmill exercise. Immediately following treadmill exercise, in situ TA muscle function assay was performed to measure contractile properties of the TA muscles and compared to non-exercised mice. Without R16/17 protein transfer, treadmill exercise caused significant reduction of specific twitch force (a), but with R16/17 protein transfer, specific twitch force was maintained (b)

Back to article page

Molecular Medicine

ISSN: 1528-3658