TY - JOUR AU - Li, Gang AU - Fan, Liping AU - Wang, Yuqing AU - Huang, Li AU - Wang, Meijuan AU - Zhu, Canhong AU - Hao, Chuangli AU - Ji, Wei AU - Liang, Hansi AU - Yan, Yongdong AU - Chen, Zhengrong PY - 2019 DA - 2019/08/09 TI - High co-expression of TNF-α and CARDS toxin is a good predictor for refractory Mycoplasma pneumoniae pneumonia JO - Molecular Medicine SP - 38 VL - 25 IS - 1 AB - Early distinction between refractory M. pneumoniae pneumonia (RMPP) and non-RMPP (NRMPP) is still difficult. The community-acquired respiratory distress syndrome (CARDS) toxin can induce inflammatory and histopathological phenotypes associated with M. pneumoniae infection. This study aimed to investigate the clinical significance of CARDS toxin and pro-inflammatory cytokines in children with RMPP and to explore whether CARDS toxin can induce TNF-α expression. SN - 1528-3658 UR - https://doi.org/10.1186/s10020-019-0105-2 DO - 10.1186/s10020-019-0105-2 ID - Li2019 ER -