Table 3 Significantly enriched BP GO terms in active protein modules of DCresistant sub-network
BP GO term | Count | FDR corrected P-value |
|---|---|---|
Turquoise module | ||
 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 33 | 1.05E-58 |
 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 32 | 2.26E-57 |
 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 32 | 3.66E-57 |
 positive regulation of protein ubiquitination | 34 | 1.08E-54 |
 ubiquitin-dependent protein catabolic process | 36 | 9.37E-41 |
 proteolysis | 37 | 3.94E-27 |
Brown module | ||
 mitochondrial ATP synthesis coupled electron transport | 12 | 1.82E-17 |
 mitochondrial electron transport, NADH to ubiquinone | 11 | 4.66E-17 |
 respiratory electron transport chain | 12 | 5.11E-17 |
 electron transport chain | 13 | 9.51E-16 |
 oxidative phosphorylation | 12 | 9.11E-15 |
 mitochondrion organization | 6 | 1.17E-04 |
Yellow module | ||
 positive regulation of programmed cell death | 9 | 2.59E-03 |
 MAPKKK cascade | 6 | 2.59E-03 |
 protein amino acid phosphorylation | 10 | 2.59E-03 |
 response to stimulus | 24 | 2.59E-03 |
 programmed cell death | 9 | 3.68E-03 |
Green module | ||
 RNA splicing | 8 | 6.09E-05 |
 regulation of acetyl-CoA biosynthetic process from pyruvate | 3 | 1.31E-04 |
 spliceosomal snRNP assembly | 3 | 1.61E-03 |
 response to DNA damage stimulus | 7 | 1.80E-03 |
 nuclear mRNA splicing, via spliceosome | 4 | 1.92E-03 |
 glycolysis | 3 | 3.52E-03 |
Red module | ||
 tRNA aminoacylation | 8 | 1.50E-11 |
 tRNA aminoacylation for protein translation | 8 | 1.50E-11 |
 translation | 9 | 1.88E-06 |
Pink module | ||
 fatty acid oxidation | 6 | 7.26E-10 |
 peroxisome organization | 5 | 3.55E-09 |
 protein targeting to peroxisome | 3 | 1.37E-05 |
 fatty acid beta-oxidation using acyl-CoA oxidase | 2 | 2.84E-04 |
 acyl-CoA metabolic process | 2 | 1.94E-03 |
 mitochondrion organization | 3 | 4.30E-03 |