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Fig. 3 | Molecular Medicine

Fig. 3

From: Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis

Fig. 3

Melatonin improves femoral and vertebral (L1) changes, body weight, and organ index in osteoporosis (OP) mice. Effects of treatment with melatonin at different doses on body weight (a), organ index (b), femur diameter (c), femur length (d), vertebra diameter (e), and vertebra height (f). Control: normal mice, Model: retinoic acid (RA)-induced OP model mice, Mlt-L: low-dose melatonin-treated OP model mice, Mlt-H: high-dose melatonin-treated OP model mice. Positive control: alendronate-treated OP mice. *, P < 0.05 vs control. #, P < 0.05 vs model; n = 6 per group

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