Fig. 8
From: Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis
Melatonin improves oxidation in osteoporosis (OP) mice. Oxidative stress-related liver superoxide dismutase (SOD) (a), malondialdehyde (MDA) (b), and glutathione peroxidase (GPX) (c); left kidney SOD (d), MDA (e), and GPX (f); and right kidney SOD (g), MDA (h), and GPX (i) were determined after the administration of melatonin or alendronate for 2 months. Control: normal mice, Model: retinoic acid (RA)-induced OP model mice, Mlt-L: low-dose melatonin-treated OP model mice, Mlt-H: high-dose melatonin-treated OP model mice. Positive control: alendronate-treated OP mice. *, P < 0.05 vs control. #, P < 0.05 vs model; n = 6 per group